150K Hair Follicle Serum
2023 NewBeauty Award Winner "BEST HAIR GROWTH SERUM"
The human scalp contains up to 150,000 hair follicles. The 150K Hair Follicle Serum takes care of all of them. No Follicle Left Behind!
The 150K Hair Follicle Serum is a rejuvenation-inspired, super-charged scalp serum. It works by revitalizing the environment surrounding the hair follicles, creating an optimal ecosystem to help the follicles flourish.
Contain 48 proven active ingredients. Drug and hormone free.
Patented technology.
US Patent No. 11,260,013.
GETTING TO THE ROOT OF HEALTHY HAIR
What It Does
- Renews the look of hair volume, quality, and texture. Improves overall visible hair health.
- Helps reduce signs of shedding and hair falling out
- Promotes sustainable scalp health and wellness.
- Revives follicle nutrition support, nourishes blood irrigation.
- Revives the natural moisture of the scalp and hair roots.
- Promotes the scalp barrier and immunity, optimizes the delicate ecology of the scalp.
- Rejuvenates the smoothness of the scalp.
- Minimizes the look of pigmentation and discolorations of the skin under the hair.
- Helps improve the appearance of inflammation and itchiness of the scalp.
- Addresses the appearance of grey hair and visibly softens the hair color at the roots.
Why It Is Different
Our serum is an excellent cosmeceutical care for the scalp. We’ve paired an advanced and targeted treatment with an established and validated science to bring you a product that is unlike any other on the market. Here’s what makes the 150K Hair Follicle Serum different.
- Based on the natural rejuvenation power of our body.
- Evolved from proven science and is patent-protected.
- Studied in an independent, third-party clinic.
- Contains the BioSerum-level of Defensin-molecules.
- Contains 48 proven natural ingredients, shown clinical efficacy on scalp and hair. All ingredients are infused at their clinical performance concentration.
- Free from drugs and hormones.
- Can be combined with Rogaine, minoxidil or any other treatments including microneedling with PRP.
- Lightweight, water-based formula with minimal addition of stabilizing ingredients.
- Supplied in an innovated ampule that protects the serum’s integrity. The applicator allows convenient “no product wasted”-dosing directly to the hair roots, right to the hair follicles.
- Non-irritating and gentle on sensitive scalp.
What Users Also Found the 150K Hair Follicle Serum Can Be Good For
- Menopause- and COVID-related hair loss: “I love this stuff! My hair was falling out from Covid and menopause, this stuff is making it grown back at record speed!” Rebecca, a Verified Buyer
- For thinning hair on the temple: "Worked on thinning temple: My hair was thinning at the temple. I wasn’t willing to use rogaine, but decided to give this a try in that area only. One drop, twice daily, for 3 months. I saw improvement after just a few weeks, which encouraged me to go the recommended 3 months. Still using it. Hair has filled in again, very pleased.” Elizabeth, a Verified Buyer
- New Hair Growth: "I have been using the hair system for 2 months now and def starting to see new growth occur where applied." Ashlee, a Verified Buyer
- Decrease in Hair Falling Out: "I am Impressed! I have only been using the 150K Hair Follicle Serum for a month. I am experiencing less hair fall." Valerie, a Verified Buyer
- Reduce Hair Shedding: "I have been using the 150K 1-2 times/day; 3 pumps for about 2 weeks. Just prior to starting on it I had been concerned about the shedding I was experiencing; it was more than usual. I now have almost no shedding, my scalp feels more hydrated and I had a rough spot that has softened; my hair feels overall healthier and I have already received some compliments!" M., a Verified User
- For Dry and Itchy Scalp: " I am thrilled with DefenAge hair follicle serum as I no longer have an itchy scalp. For many years I suffered from a very dry scalp. I've tried numerous products and none have worked now. I will continue to use the hair follicle serum along with many other DefenAge products." Terri, a Verified Buyer
- For Eyebrows: " I had a bad eyebrow wax and my eyebrows were like pencils. My aesthetician suggested using this on my brows while I grew them back out (I have thyroid issues and I lived through the 90’s/00’s eyebrow plucking decades- all which make my brows thin). I must say- I’m happily surprised as to the growth. It’s not like I now have a chia pet on my brows or anything, but they are thicker and I swear I have hairs where I never used to pluck (and for once that is a good thing)." Christine, a Verified Buyer
Size Options
3 MONTH SUPPLY
1 dispenser with ampule x 1.0 fl. oz., and 2 refill ampules 1.0 fl. oz. each
SKU 10983
1 MONTH SUPPLY
1 dispenser with ampule x 1.0 fl. oz.
SKU 10532
REFILL AMPULE
1 fl. oz.
SKU 10534
Scientific Background
“Pre-clinical research shows that the topical application of human defensins in the research models leads to enhanced hair production through the augmentation of key Wnt transcripts1 and stimulation of the blood supply through the stimulation of angiogenesis2, - Gregory Keller, MD, FACS”
References
1. Lough et al. Plastic and Reconstructive Surgery. 2013, 132(5): 1159-1171.
2. Takahashi et al. Frontiers in Immunology. 2021, 12: 712781.
Clinical Studies
The 150K Hair Follicle Serum is clinically-tested by a Board-Certified dermatologist and shows an outstanding safety profile [ hypoallergenic, non-sensitizing, non-irritating formula ].
The efficacy clinical studies show that the defensin-containing serum, applied twice daily, caused progressive normalization of visible hair-growth metrics and hair qualities, visible reduction of shedding, and normalization of scalp conditions.
Improvement in Scalp Quality and Visible Hair Coverage
Clinical photos are obtained from the study performed by an independent, third-party clinic. Photos have not been retouched.
Complete Switch from "Hair Loss" to "Hair Growth" Ratio
Clinical data is obtained from the study performed by an independent, third-party clinic.
Visible Hair Shedding Reduction
Clinical data is obtained from the study performed by an independent, third-party clinic.
Increase in Visible Hair Volume
Clinical data is obtained from the study performed by an independent, third-party clinic.
Increase in Visible Hair Presence
VISIBLE HAIR GROWTH SPEED TEST: One week after completely shaving with razor:
Clinical photos are obtained from the study performed by an independent, third-party clinic. Photos have not been retouched.
Increase in Visible Beard Density
VISIBLE BEARD GROWTH SPEED TEST: One week after completely shaving with razor:
Clinical data is obtained from the study performed by an independent, third-party clinic.
PROFESSIONAL OPINIONS
Vivian Bucay, MD
Dermatologist
What Aesthetic Doctors Are Excited About in 2023.
Prime Magazine, 2023, Vol. 13 (1).
As a longtime fan of DefenAge, I knew it was just a matter of time before this technology was leveraged to treat hair loss. The 150K Hair Follicle Serum is a water-based formulation that contains age-repair defensins paired with other ingredients (including organic pea sprout, azalea-isolated yeast extract, and microalgae extract) to optimise the environment surrounding hair follicles.
I was impressed by the pilot study results that showed a 64% decrease in hair shedding after 3 months, along with an increase in the percentage of anagen hairs of 25% at baseline to 85% at 3 months. This combination of decreased shedding with an increase in the percentage of actively growing hair leads to visible improvement in anyone suffering from hair loss or thinning. I also like that this serum can be combined with other proven topical treatments, such as Minoxidil, Rogaine, and others.
Another benefit that patients appreciate with this product is that it is a true multi-tasker. It can be used effectively for treating the beard area, thinning eyebrows, and helps to rejuvenate the scalp and skin under the hair. It is lightweight, gentle on the scalp and hair, non-irritating even for patients who are sensitive, and easy to apply.
The unique DefenAge serum is patent-protected and contains the BioSerum-level of Defensin-molecules, which is the brand’s hero product. It contains 48 proven natural ingredients that have been shown to have clinical efficacy on the scalp and hair.
The serum is supplied in an elegant silver ampule that looks very chic. Our patients are committed to using this formulation long-term because it is user-friendly and they see results.
Anetta Reszko, MD
Dermatologist
New In My Practice.
Modern Aesthetics, 2023.
New York City dermatologist Anetta Reszko, MD, PhD, discusses why she recommends Defenage’s 150K Hair Follicle Serum PRO for thinning hair.
WHAT IS DEFENAGE’S 150K HAIR FOLLICLE SERUM?
The Defenage 150K Hair Follicle Serum is a fast-absorbing, highly potent serum that treats the scalp and hair follicles, restoring their youthful state. The serum prevents shedding, rebalances the scalp microbiome, and strengthens the hair follicles.
The product is brand new on the market. I have been using it regularly on my scalp and recommend it to my clients at my private practice in New York City. The formula contains proprietary potent defensin molecules, which signal the body to strengthen existing follicles by activating dormant natural reserves and increasing blood and nutrition supply. In addition to defensins, it contains potent antioxidants, algae extracts, vitamins, anti-inflammatory mediators, and peptides that target various parts of hair miniaturization and the hair loss process.
HOW DO YOU SUGGEST THAT YOUR PATIENTS USE THIS PRODUCT?
Consistency is key for best results. Use several pumps of the product on clean scalp. Unlike other products that might cause scalp irritation and dryness, 150K Hair Follicle Serum is well tolerated and non-irritating. It also won’t leave hair greasy.
WHAT TYPE OF RESULTS ARE YOUR PATIENTS SEEING WITH REGULAR USE?
Patients are seeing thicker, more voluminous hair with less shedding and breakage. It is great to use on the beard and eyebrows as well.
WHAT PROCEDURES DOES THIS PRODUCT COMPLEMENT?
The Defenage 150K Hair Follicle Serum complements in-office treatments such as platelet-rich plasma injections and scalp microneedling. The serum is also safe and effective to use with prescription minoxidil.
Dr. Reszko disclosed no relevant financial interests.
REAL PEOPLE ARE SAYING
-
★★★★★
"My husband has started this product and in a couple of weeks is already starting to see progress and improvement in his hair growth. His scalp also looks healthier, which is hard for him to see but is noticeable to me!""
Susan, a Verified Buyer
-
★★★★★
"I've been using this serum about 3 weeks now. There's a section near my bangs that seems to be thinning and that's where I put the serum every night. Starting to see new growth."
Lisa, a Verified Buyer
-
★★★★★
"I have been using this serum for a month and can already see a difference in my hair. I notice fine new hairs starting come in and my scalp is less dry. The serum is easy to use."
Gloria, a Verified Buyer
-
★★★★★
"I have been using the 150K Hair Follicle Serum for over a month and am happy with the results. The scalp is healthier, and I experience less hair loss. Therefore, I am planning to continue using the serum."
Carmen, a Verified Buyer
-
★★★★★
"I am thrilled with Defenage hair follicle serum as I no longer have an itchy scalp. For many years I suffered from a very dry scalp. I've tried numerous products and none have worked now. I will continue to use the hair follicle serum along with many other Defenage products."
Terri, a Verified Buyer
-
★★★★★
"I am Impressed! I have only been using the 150K Hair Follicle Serum for a month. I am experiencing less hair fall."
Valerie, a Verified Buyer
-
★★★★★
"Worked on thinning temple: My hair was thinning at the temple. I wasn’t willing to use rogaine, but decided to give this a try in that area only. One drop, twice daily, for 3 months. I saw improvement after just a few weeks, which encouraged me to go the recommended 3 months. Still using it. Hair has filled in again, very pleased."
Elizabeth, a Verified Buyer
-
★★★★★
"Using it for eyebrows: I had a bad eyebrow wax and my eyebrows were like pencils. My aesthetician suggested using this on my brows while I grew them back out (I have thyroid issues and I lived through the 90’s/00’s eyebrow plucking decades- all which make my brows thin). I must say- I’m happily surprised as to the growth. It’s not like I now have a chia pet on my brows or anything, but they are thicker and I swear I have hairs where I never used to pluck (and for once that is a good thing)."
Christine, a Verified Buyer
-
★★★★★
"Hair growth: I have been using the hair system for 2 months now and def starting to see new growth occur where applied."
Ashlie, a Verified Buyer
-
★★★★★
"I am thrilled with Defenage hair follicle serum as I no longer have an itchy scalp. For many years I suffered from a very dry scalp. I've tried numerous products and none have worked now. I will continue to use the hair follicle serum along with many other Defenage products."
Terri, a Verified Buyer
-
★★★★★
"Less hair loss, notice areas thickening. Easy to use."
Kari, a Verified Buyer
-
★★★★★
"VERY pleased so far! I used 3 vials of this serum in about a month and have started #4. I'm very pleased... easy to apply, "
Don, a Verified Buyer
Key Performance Ingredients & Technologies
This unique formula targets all key components of scalp and hair health and is only infused with clinically established, evidence-based ingredients in their performance concentrations. Key performance ingredients:
Age-Repair Defensins® PRO | Serum Level | DefenAge's Exclusive
• Revitalize Environment Surrounding Follicles •
Defensins are natural molecules. They signal our body to create new and “fresh” cells by activating the body’s dormant reserves. They are also known as promoters of capillaries and activate nutrition supply. DefenAge contains an identical copy of human defensins made via bio-synthesis; defensins are exclusive to DefenAge.
Organic Pea Sprout Extract
• Rejuvenates Hair Life-Cycle •
Targets and optimizes the core of hair health. Boosts visible hair thickness.
Azalea-Isolated Yeast Extract
• Regenerates Visible Hair Density •
Optimizes the energy of the follicle cells, balances surrounding signaling molecules, and activates cell “memory.” The unique yeast strain, Pichia minuta, is rich in peptides, and isolated from flowers of azalea; it is converted into powerful cosmeceutical activity using advanced biotech-born technology.
Microalgae Extract
• Boosts Visible Hair Strength and Volume •
Keeps skin calm. Strongest, fastest, most effective soothing ingredient from the sea.
Vitamin B Complex | Niacinamide & Biotin
• Hydration • Circulation • Keratin •
Niacinamide (vitamin B3) and biotin (vitamin B7) are vital components of the hair-supporting system. The vitamins in this complex repair the natural moisturization of the scalp and cells surrounding the follicles, revive follicle oxygen supply, activate in-hair keratin, and enhance the appearance and feel of hair. Each vitamin B3 and B7, are present in two different forms in this formula to guarantee maximum benefits.
Antioxidant Complex
• Visible Hair Re-pigmentation • Oxidative Stress Relief •
The advanced detoxifying complex concentrate helps suppress free radicals and educates follicles to recover original natural color. The components of the complex are shown to reduce visible density of grey hair on the scalp and visibly soften hair color at the roots. The complex contains the bio-mimic to the naturally present in the body peptide, palmitoyl dipeptide-52, two phyto-extracts from the root of Spiny restharrow and black oat seeds, and vitamin E.
Fine Blend of Soothing and Calming Ingredients
• Scalp Calming and Soothing •
This formula is infused with a powerful and concentrated composition of soothing and calming botanical molecules, including extract from the flowers of ‘love in a puff’, a medical plant known as a cortisone-free alternative, Epigallocatechin Gallatyl Glucoside, a water-soluble form of one of the most active molecules found in green tea, and black currant seed extract.
Complex of Natural Boosting Ingredients and Technologies
• Overall Scalp and Follicle Health • Follicle Irrigation • Scalp Microbiome •
Our “know-how”-protected, advanced and powerful collection of proven scalp- and hair-supporting and revitalizing ingredients, includes natural flavonoid Apigenin, extracts from turmeric, celery seeds, apples and sugar cane, and water-friendly form of castor oil.
This complex provides purity and comfort for scalp, supports healthy scalp microbiome and nourishes its delicate ecology, and promotes your own defensins.
CLEAN SKINCARE
The cleanliness of our products is DefenAge’s philosophy. We do not use “convenient” ingredients that have compromised safety, and before we add any component into our formulas, we perform comprehensive research around it. To review the full list of ingredients that are excused from DefenAge, please go to our Clean Beauty page. In addition, this product does not contain fragrance.
GREEN PLANET
The box is fully recyclable, please recycle. We do not test products on animals.
INGREDIENT LIST
Water (Aqua), Pentylene Glycol, Butylene Glycol, Niacinamide, Dimethyl Isosorbide, Caprylic/Capric Triglyceride, Octyldodecanol, Glycerin, Alpha-Defensin 5, Beta-Defensin 3, Hexapeptide-11, Palmitoyl Dipeptide-52, Biotinoyl Tripeptide-1, Biotin, Curcuma Longa (Turmeric) Rhizome Extract, Pisum Sativum (Pea) Sprout Extract, Apium Graveolens (Celery) Seed Extract, Cardiospermum Halicacabum Flower / Leaf / Vine Extract, Camellia Sinensis Leaf Extract, Rosemarinus Officinalis (Rosemary) Leaf Extract, Isochrysis Galbana Extract, Avena Strigosa Seed Extract, Pyrus Malus (Apple) Fruit Exract, Citrus Limon (Lemon) Fruit Extract, Saccharum Offinarum (Sugar Cane) Extract, Ononis Spinosa Root Extract, Yeast Extract, Ribes Nigrum (Black Current) Seed Oil, Helianthus Annus (Sunflower) Seed Oil Unsaponifiables, Helianthus Annuus (Sunflower) Seed Oil, Leuconostoc / Radish Root Ferment Filtrate, Betaine, Tocopherol, Tocopheryl Nicotinate, Tocopheryl Acetate, Ubiquinone, Apigenin, Oleanolic Acid, Glycogen, Epigallocatechin Gallatyl Glucoside, Sodium Stearoyl Glutamate, Methyl Glucose Sesquistearate, Ammonium Acryloyldimethyltaurate / VP Copolymer, Phospholipids, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, I-Alanyl-I-Glutamine, Maltodextrin, Gellan Gum, Sodium Phytate, Albumin, Phytic Acid, Potassium Sorbate, Hexylene Glycol, Phenoxyethanol, Sodium Benzoate, Sodium Chloride.
Fragrance free.
Press Release
DefenAge® Skincare Announces 150K Hair Follicle Serum
Patented Technology with Age-Repair Defensins Optimizes the Scalp and Skin Under the Hair for Overall Hair Health
Carlsbad, CA – October 19, 2022 – DefenAge® Skincare, manufacturer and distributor of revolutionary, evidence-based, anti-aging products, announces the launch of its first hair-centric product, the 150K Hair Follicle Serum.
The eagerly awaited and scientifically-advanced formula contains a concentrate of DefenAge’s proprietary Age-Repair Defensins. Defensin-molecules are proven to stimulate the skin’s latent master cells and spark a targeted, regenerative response. This technology is covered by US Patent No. 11,260,013, entitled “Compositions and Methods for Providing Hair Growth,” and is exclusive to DefenAge.
The light, water-based innovative formula is also infused with an outstanding collection of 48 proven revitalizing ingredients, shown to have clinical efficacy on the scalp and hair, including the natural flavonoid Apigenin, azalea flower-isolated yeast extract, and organic pea sprouts extract. The formula is drug and hormone free.
No Follicles Left Behind
Rejuvenation-inspired, the 150K Hair Follicle Serum is designed for both men and women to revitalize the scalp and skin under the hair. The human scalp contains up to 150,000 hair follicles. DefenAge 150K Hair Follicle Serum ensures that each and every one of those follicles functions optimally. The proprietary technology keeps the skin fresh and healthy, providing an ideal environment for hair follicles to flourish.
This revolutionary serum helps reduce visible signs of shedding on the head, promotes the immunity of the scalp, and nourishes follicle nutrition support to encourage healthy hair. Applied directly to the scalp via a special vial that protects product integrity and prevents waste, the serum aims to re-establish the visible quality of the hair and preserve natural pigmentation, mitigating gray hairs.
“During initial testing, we also found that the new serum provides remarkable benefits if applied on the skin under the beard,” – said DefenAge’s CEO, Nikolay Turovets. “We saw that the skin under the beard becomes visibly smoother and more evenly toned, and the appearance of inflammation and itchiness is reduced. The 150K Hair Follicle Serum is the perfect complement to attaining visibly healthy skin under the beard while promoting full and lush hair.”
Due to its high concentration of defensins, the DefenAge PRO EXCLUSIVE Platinum Edition will only be available through professional offices and is not purchasable online or via social media.
Backed by Science and Clinical Studies
“Pre-clinical research showed that the topical application of human Defensins in the research models leads to enhanced hair production through the augmentation of key Wnt-transcripts and stimulation of the blood supply through the activation of angiogenesis,” shares facial plastic surgeon, Dr. Gregory Keller, MD, FACS. "The medical aesthetic community has been buzzing about this product for a long time, and we are thrilled that it’s finally here.”
In clinical pilot studies, the Defensin-containing serum revealed the progressive normalization of visible hair-growth metrics and hair qualities, visible reduction of shedding, and normalization of scalp conditions over the course of 1-, 2-, and 3- months.
The product is available in an enhanced professional formulation [ PRO EXCLUSIVE Platinum Edition ] through select dermatology and plastic surgeon offices, and med spas.
How To Use
Designed to rejuvenate the scalp, keeping it fresh and healthy. Provides an optimal environment to help hair follicles perform their best. Please follow the directions below for optimal results.
1.
With cap on, shake the bottle well before the first use.
Take off cap, move buttons into unlocked position.
2.
Twice daily, in the morning and evening, by squeezing the bottle's "wings", apply 2-3 pumps of the serum across a moist or dry scalp. Working in small sections, press the tip of the applicator directly onto the scalp and squeeze the wings to release small dots of serum.
3.
Using fingertips, gently massage the serum into the hair roots, concentrating on areas of concern. Do not wash-out (leave product on).
TIP
Be sure that the scalp serum is applied on problem areas, including areas with poor hair growth, bald patches, areas with grey hair, and on hair part.
Replacement of the Refill Cartridge
1.
Take off the cap of the refill.
2.
Insert the refill bottle into empty "wings" bottle.
Push and squeeze the wings until it clicks. Your bottle is ready to use.
For more information please contact your DefenAge Sales Professional or
our professional support service at
[email protected] or (844) 397-2697