The Skin You Had.
The Science to
Get It Back.
DefenAge PRO Exclusive is not available in stores or online. It's only available through your provider's office — because that's exactly where results like these belong.
Recommended by Leading Physicians
Trusted by 600+ dermatologists, plastic surgeons, and aesthetic specialists nationwide. DefenAge PRO is dispensed only through licensed providers who recommend it after rigorous review of its clinical results.
This Is Not Your Average Skincare
DefenAge PRO Exclusive is a provider-dispensed line formulated with enhanced defensin peptides available only through your provider. It exists in one place: your provider's office.
Enhanced Defensin Concentration
The Platinum Edition contains a higher concentration of Age-Repair Defensins® than anything available at retail — formulated specifically for provider-supervised use.
Exclusive to PRO lineAvailable Only Through Your Provider
No online stores. No gray market. No worrying about counterfeit products. Your provider's office is the only place to get the real Platinum Edition — and that's intentional.
In-office exclusiveBacked by Published Research
30+ clinical studies, with key findings published in peer-reviewed journals including the Journal of Drugs in Dermatology. Real clinical data, real patients, real results — not marketing claims.
Peer-reviewed scienceYour Skin Already
Knows How to
Renew Itself.
We just give it more of what it needs.
Inside your body are natural peptides called defensins. They help support your skin's natural renewal process. When you're young, your body makes plenty of them. As you age, production slows — and your skin shows it.
DefenAge delivers patented Age-Repair Defensins® peptides directly to your skin, supporting your skin's own renewal process, without irritation.
Your skin has a built-in renewal system
Defensins are natural signaling peptides that support your skin's ability to produce fresh, healthy skin. It's a process your body has always had.
Aging slows that system down
Defensin production declines with age. Your skin's renewal process slows, and the visible signs of aging appear — lines, loss of firmness, uneven tone.
DefenAge PRO restores the signal
Our patented Age-Repair Defensins® peptides replenish what time has depleted — supporting your skin's own renewal process, without irritation.
Age-Repair Defensins® are patented. No other skincare brand uses these peptides — retail or otherwise.
The DefenAge PRO Lineup
Bestseller8-in-1 BioSerum
Eight serums in one formula. Lines, pores, firmness, tone — all addressed in a single daily step.
Learn More →
24/7 Barrier Balance Cream
Rebuilds and fortifies your skin barrier while delivering deep, lasting hydration morning and night.
Learn More →
KitClinical Power Trio
The recommended starting point. BioSerum + Barrier Balance Cream + Reveal Masque — the core three.
Learn More →
New5+ Defensin Recovery Serum
Formulated for recovery. Calms, soothes, and supports recovery after aesthetic procedures.
Learn More →See the Difference
Actual patients from the 2018 Journal of Drugs in Dermatology clinical study. Photographed before starting the DefenAge regimen and after 12 weeks. No filters. No retouching.
Individual results may vary. Photos taken under consistent lighting by independent clinical evaluators. Patients used the full DefenAge regimen daily for 12 weeks. Click any photo to enlarge.
The Numbers Behind the Results
From peer-reviewed clinical studies published in the Journal of Drugs in Dermatology. Real patients, independent evaluation.
Fabi S, Taub AF. Journal of Drugs in Dermatology. 2023;22(9). 20 subjects, 90-day protocol, IRB-approved (NCT05082766). Regimen: DefenAge PRO Exclusive 8-in-1 BioSerum, 24/7 Barrier Balance Cream, 3D Eye Radiance Cream, 1-Step Multi-Cleanse. Individual results may vary.
What Are You Looking to Address?
Every DefenAge PRO product is designed around what you see in the mirror. Find what fits your skin's needs.
Wrinkles & Fine Lines
BioSerum, Barrier Balance Cream, Neck Cream, Eye Cream
Explore →Firmness & Laxity
BioSerum, Barrier Balance Cream, Neck Cream, Body Cream
Explore →Dark Spots & Pigmentation
BioSerum, Barrier Balance Cream, Reveal Masque
Explore →Pores & Texture
BioSerum, Reveal Masque, Multi-Cleanse
Explore →Dullness & Radiance
BioSerum, Barrier Balance Cream, Reveal Masque
Explore →Dryness & Hydration
Barrier Balance Cream, Eye Cream, Body Cream
Explore →Post-Procedure Recovery
5+ Recovery Serum, Pre & Post Procedure Kits
Explore →Hair Thinning
150K Hair Follicle Serum PRO
Explore →“DefenAge really represents a major advanced paradigm shift seen once per decade. The science is remarkable.”
Ready to Experience the Difference?
DefenAge PRO Exclusive products are only available through authorized medical aesthetic providers. Find one near you and take the first step toward the skin you remember.
Find a Provider Near YouEnter your zip code to see authorized DefenAge PRO providers in your area